SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b231f9d8bfc0f543415a7371aa0df638cad08fa83c00f2319f56068f1b3df049' 
  AND token = 'PbALALyArFMV92v6y/sToqS9VUTyWpRG7b/Gmzadk10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}