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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ce33ccce14e5c7d30a79994b971f10e7b51b5f03743e5dede51a0aec392a35' 
  AND token = 'LAF66RCRlY0+kiKzLOGDKuEEulXAEsS2OmHeNB+AlcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}