SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38119b04698ac559ed65aa63079e0d5d78498645c64a55fb496c8e4c983f1372' 
  AND token = 'FSS4+wb/cXpm0mJFhIhpT8i2jJmMVUm3p5Y2ELTRHK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}