SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37c46c2e4f6d42af33720fece82ed7d3e60345002ca42bf1d96125735a43d182' 
  AND token = 'aEfc9BHDGr53mbiLUAqDQ0R5D4c+bdpaS2MNtWzO3Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00094

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}