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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744d7eece41a683637f57560f3396df67490243ebd7a377f67557705161a0c2a' 
  AND token = 'yGnihIHerVXhrMpIyx9CZaFuy+kyOOXpKMPTpJm6i2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}