SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e366246df9ba2f7d2c5e6546ab76c7ab38772510d3190afaa9ac600ef8f35d9f' 
  AND token = '8qpIFBwv8RAktZ4dKA0px1HwIQ7RvHu1vCiRJMLIRzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}