SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45804a48887927aa126342a77cc9e1eac54acdfc52eedc7497653c57797902ef' 
  AND token = 't1UBvjWcIF4hpYFTZV7B7VmUcAK2ufnnSJtmPnAJrkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}