SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4e61299b05b553a1ef8d4cd90865b86ca2d8cccf5f00a60a246f23751a6e02' 
  AND token = 'wm+JsyimBzgjYwku7UenoxLWyjfmc3bZUt0i4LqS+DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}