SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11271894764629f410c34fb5b630e16f64c4585f89b866c4c69c8a24a67e8ede' 
  AND token = 'HVOsYLYEGCSSb3UG4bpJCmmj/psYl2NCafRAcE8BKxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}