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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c59b2ec31c75b45563364119eccd4b81e7c85e3ae7251e82bac9574fba06ce' 
  AND token = 'WRCUSEvBVyrSRpK4+rWsKzO8ozCRTtNrkAM3zblNmkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}