SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9449849489d5f64a8e54c3dd57cf400e1ef9b5ad0075d6955af60918341e06' 
  AND token = 'czz7ISnsSfLJnYnZZNfYqXcgdrwGkFh/g+VmmuURaKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}