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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c82623ad2cff140046cca73ca471846eccf2168d12aeb4a0a266a3b8dd2e2b9' 
  AND token = '/UFktRBw7+wZM6vj+v1Tx7CfMWJyRfL/Dd0Br5Ht5m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}