SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a18669a49676e1744eb10528ea89c9bae881ca4a0c49b6b8943271b520f7f80' 
  AND token = '26LbDveN1AIxAbJBw51XtrzM3s52YkaqdQ5rm/KgzII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}