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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40657ae277c01589493fd7ef0d3e981706148be69a675d9385f762369b7ba4e1' 
  AND token = 'JUGMZNqnemPy7emnTH8xylMJ0blJ1kvD5fxKQ9KmIrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}