SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0315b91c6aae5f051e4c1a4c505039ce3da50f36f90a054ab8c94a76763ecbcd' 
  AND token = 'CIxeqA+omQ2E+6vWSo6N6UBXJ0GEKgVT6eEhLMW5mfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}