SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db49318ef584a89bac63ec688cd7f182fe8299ff458adcf41e628e2bca96543e' 
  AND token = 'e6GkfiwRCRAyc7KzCGy81v4DK8/WE06M1vaiqsUfC0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}