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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64240a7ee4d46da138d99ab1a5f6936752266a573f2d510fe4e692d4d2577e81' 
  AND token = 'LnnCf12DowTBW/ELeTTKHGIsAWfuyLvPLVJB5eQg9xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}