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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d193dfc8f49d42404f6fcea7839a47b946abbfc8cf125222e419c58b102618' 
  AND token = 'cJ1TE54n0/JKrkpR2kq1FRVxniFKsvqa8yk1FLxq9rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}