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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed663e3ff8d93109bfb178322dcd478a1940cdefba30ffbac3d56bda962da0d2' 
  AND token = 'Si0f3w6jLgBTYksVCG+Oq7N4OCQUausLB50vI5wuW6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}