SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65750cf59ba8d5e3f34efef56db1d12b034203653d9c5c39d548c2adf66ef66c' 
  AND token = 'PaMxAMldxCVqaXdeHtS6wpBcCYNKJFE32yzrrYEKrD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}