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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3cd2c0518804e0bc4e09c65ddd49e02d0cbcbb02963929853a9f8390eb5a51d' 
  AND token = 'M664/qvAMVWWjhQ0W2A9muVvJLRIy1D9+RO5FHQ7D5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}