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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c437e544a4baf1b92c2e489a1211ab932cf1c98b6f60c43ffd076f1b25e651' 
  AND token = 'AAAZHf2Ni7pBtV1Sk0EzdGSJ7YTOcbU3CnaiZbBth9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}