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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e680872050fe1a2fef7b54a7f0a78286aca0a011cf9b3f6bac5506bf1d2aac9' 
  AND token = '2gS6bd1FSC+h8IpceVI/ztsVoOGUYFsKgQbhkGe4ntc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}