SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea078a2a59e39b67507a687c39dc33e93cd9e7cfe7c293c0553f28721217a1c3' 
  AND token = '9HH+fjCs4sjyl/SVEo69JI6d7nPPYUf2FRj1Bs8RZ3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}