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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df8c1407cdb093c77022b5770a9ffeda242c40673c1f7e42a4975fa45b494606' 
  AND token = 'QW+VctdGCORrMlSFlBnWkSYqRLx+tgdtWZfWbtd3kcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}