SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08015b8a2cfec94f4a27460181fb3b73f52d92914f3edc81ca512d5581cf8d25' 
  AND token = 'oEIOi3fMe4CuxOXCLBQsdzEOsmK/p5r9aiEIwr2u8AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}