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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06b74132fe45a8dd4dd19a78f0a267ab55a004e84709502d54df83d89aeee8ec' 
  AND token = 'APvx4hoCM3Hl61B5O8w37QwoC3R+RRRLvSOZEwIGt1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}