SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bb433e4f81fecf387173df958ac36e3c60b6d5434511f07bb78df6ae543d4c9' 
  AND token = 'ECGp9n0nCbbffcHkCoud2kL4FxmcoC6s+13zFqZ2gOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}