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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cde2f006d7dacff767c7847495f9187d9142a587ed42a0bc0e92e2a177d8a0b9' 
  AND token = 'YICkmZkTqtN0dvDK2eGNzMzTaRjkFC6tKgncVvtUm8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}