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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a0a414269c4e61a2e9cac0c02e86f70bb64285940020af63eeb4509373142c2' 
  AND token = 'kwoOk+ZvomODQZfvsrjE4tt7wEHHHZNlq0IS4i7kPoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}