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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4463eb56698f75d7eb9177c5e45c1dde895abba5bbb47b7729b1ef19676dc1c' 
  AND token = '+5SjzwFKpCiAouUBizdR21NPd70HeTo02UjrDSczCwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}