SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a41bd5b2350dba64022a7ffe1ac758dac060951b036fb1d31fdc14af9e0641' 
  AND token = 'YEAjMZrQTQPYOSlkjcSPpWAzdgwOvl+A0yqiq1BtKss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}