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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c3b0935c2842805e5606d886dda6b12fb1baf2344b43a349f35e415c8f2ba9' 
  AND token = 'Oxb+QmTa/112swhdgZbkaLiZzVBD6jj7WcD1nL4ka4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}