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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb48ca1d65579aac8ed9dad0203934821b4a7e1294534ceb170bf9ad0964ff99' 
  AND token = 'Wt0Tu/M6PrrW2BM2h9ZwtdG8clXW9trMwBh3tsoZwc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}