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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580706dadb540627a3e3bed67c4b6e5e97346fda65fe1daa7314bd7e2359d398' 
  AND token = 'lNWfiyphAPmo3n2B+j+3uNJMQV66rR6ek9LcjngkEhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}