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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86e0da3f3d53b534a1df6a7c0042f9a3ae411db877c18ae3e88d7a3fe0f26e46' 
  AND token = 'PCo5aY4vnZAlOM2prTWmyLQYXJhQvhntphYRIV9gmEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}