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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e37449bc5780233fcd21c94027632bb496ecb1097739936fbadf4d3f69cc21ac' 
  AND token = '9ll+SsR5U9Q+IJI3fGKD6SR5Gr+tWXraKXVGcPTYaRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}