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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a084cef563ec1bc367b2c719e901191b7979a8ead038cf33f5d4f730b55df2' 
  AND token = 'M4U6pRz0RYdXVajjBd8nfXnSlokR0avPrbIOn/FicBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}