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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785ffb0c178bb5f95cad645cb097de0158265f93347aa7dd2d20148045bd0531' 
  AND token = '5RNQQipKKcxLMsTtKte7jCtZXHlxxhN0+q7xSwVQm2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}