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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8af0b050a55e9ab711af8dc69b08ce048c03ad6b9afc5d6d9f33f1d4354f691b' 
  AND token = 'IqllSbP46xxWJmDverO35LXCC8aRKRl0zdqDjqLYKF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}