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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ffbc1347e1ea99e74190da0633b6743557d31777c46d6880f913f2a24cab77' 
  AND token = 'nERwmvRsFV98zxayD06/7IhN3r4NL+DofjgTb0ohALw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}