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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ed3dc9a96ec819c3cad1dda5d965d54f550ff7dd13096356927f772207275cc' 
  AND token = 'bfXT0PBPh3w7zkwMfmnKIFBCwCz6i6CAOTT8vxp2nP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}