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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb216fc306d608d7cfd59f66ac72d7bd26bd3731d4e3307ba378207ffbae553' 
  AND token = 'h4tTtHyJrUQggT1T+5VKoPAQrbv7JHrhq1DxnB3kOkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}