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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08e221a5a791c0c4a8c37c29dad5ba9efd9abb89b2d628cf05960c2c7e86c2a7' 
  AND token = 'FcDzZ8lPNSsSAY5DMKINXJTcSwJGN7ZVmFwDLorZln0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}