SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2866a0ea847f33b89943a580a9e005de11a60f1be47a80bdc224bdc26bcd24dd' 
  AND token = 'eIpXT2IUsARsnlsTEqvRvuh+EyETyvp9xufWleLZo6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}