SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5328fc2e16d742553c0d216ede83c75bc3776a22060c63a13b7cfdc4cbad24f2' 
  AND token = '0lWN/yp5iX4GFIg8Cjw2D/qVmpIhP3tBhlVy9ekHT+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}