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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389b97dda5adf20a4ef5a2b75732de8a5a53de3a23f388dab2c27a0f9b0d4af8' 
  AND token = '2EXWpXR54z+xhyqojHogUIReew2tXqtRZnwcdEg07hY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}