SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6a80d9d3019b4a8959d0b87c78d4739e3b8014188f15eeee028a7c6e8821921' 
  AND token = '1qqFppou1wLgujiMBc5MzQBbZaR6jvhrdPa5a8nt+ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}