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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ce6027f150ef84cee01e1d00175fab9ce2019b80010321cd628e1538a6bc36' 
  AND token = 'l7lMlo/bTqS8p+osV+I0QxyEc11MQ7bVOwvpLN+pDhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}