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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b4c1e9568b103861da7d20165f31c6d5679abcfe2025a2d809290035e0918c' 
  AND token = 'wR+8JUmfRYk6jt96r3qhvPhdRz/LQ5AlIrJEIhn6kyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}